Heterogeneity of cortical pTDP-43 inclusion morphologies in amyotrophic lateral sclerosis

Heterogeneity of cortical pTDP-43 inclusion morphologies in amyotrophic lateral sclerosis

Abstract Background Despite the presence of significant cortical pTDP-43 inclusions of heterogeneous morphologies in patients diagnosed with amyotrophic lateral sclerosis (ALS), pathological subclassification is routinely performed in the minority of patients with concomitant frontotemporal dementia...

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Bibliographic Details
Main Authors: Rachel H. Tan, Heather McCann, Claire E. Shepherd, Monica Pinkerton, Srestha Mazumder, Emma M. Devenney, Gabrielle L. Adler, Dominic B. Rowe, Jillian Kril, Glenda M. Halliday, Matthew C. Kiernan
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Acta Neuropathologica Communications
Subjects:
Amyotrophic lateral sclerosis
Frontotemporal lobar degeneration
pTDP-43
Online Access:https://doi.org/10.1186/s40478-023-01670-2

Internet

https://doi.org/10.1186/s40478-023-01670-2

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