Chromatin remodelers couple inchworm motion with twist-defect formation to slide nucleosomal DNA.
ATP-dependent chromatin remodelers are molecular machines that control genome organization by repositioning, ejecting, or editing nucleosomes, activities that confer them essential regulatory roles on gene expression and DNA replication. Here, we investigate the molecular mechanism of active nucleos...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2018-11-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC6237416?pdf=render |