OncoPeptVAC: A robust TCR binding algorithm to prioritize neoepitope using tumor mutation (DNAseq) and gene expression (RNAseq) data
Neoepitopes are tumor-derived immunogenic peptides that arise from intracellular proteolytic processing of somatic mutation in protein coding genes. These peptides bind HLA Class I proteins and are presented on the surface by antigen presenting cells. Productive engagement of HLA Class I-bound pepti...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Science Planet Inc.
2017-12-01
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| Series: | Canadian Journal of Biotechnology |
| Online Access: | https://www.canadianjbiotech.com/CAN_J_BIOTECH/Archives/v1/Special Issue-Supplement/cjb.2017-a208.pdf |