GRAY AND WHITE MATTER DEMYELINATION AND REMYELINATION DETECTED WITH MULTIMODAL QUANTITATIVE MRI ANALYSIS AT 11.7T IN A CHRONIC MOUSE MODEL OF MULTIPLE SCLEROSIS
Myelin is a component of the nervous system that is disrupted in multiple sclerosis, resulting in neuro-axonal degeneration. The longitudinal effect of chronic cuprizone-induced demyelination was investigated in the cerebral gray and white matter of treated mice and the spontaneous remyelination upo...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2016-10-01
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Series: | Frontiers in Neuroscience |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnins.2016.00491/full |