Suicide gene therapy by canine mesenchymal stem cell transduced with thymidine kinase in a u-87 glioblastoma murine model: Secretory profile and antitumor activity

The role played by certain domestic species such as dogs as a translational model in comparative oncology shows great interest to develop new therapeutic strategies in brain tumors. Gliomas are a therapeutic challenge that represents the most common form of malignant primary brain tumors in humans a...

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Bibliographic Details
Main Authors: Antonio J. Villatoro, Cristina Alcoholado, María del Carmen Martín-Astorga, Nuria Rubio, Jerónimo Blanco, Cristina Pilar Garrido, José Becerra
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8846542/?tool=EBI