MiRNA-146a/AKT/β-Catenin Activation Regulates Cancer Stem Cell Phenotype in Oral Squamous Cell Carcinoma by Targeting CD24

MiRNA-146a/AKT/β-Catenin Activation Regulates Cancer Stem Cell Phenotype in Oral Squamous Cell Carcinoma by Targeting CD24

CD44highCD24low population has been previously reported as cancer stem cells (CSCs) in Oral Squamous Cell Carcinoma (OSCC). Increasing evidence suggests potential involvement of microRNA (miRNA) network in modulation of CSC properties. MiRNAs have thus emerged as crucial players in tumor development...

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Bibliographic Details
Main Authors: Sangeeta Ghuwalewala, Dishari Ghatak, Sumit Das, Stuti Roy, Pijush Das, Ramesh Butti, Mahadeo Gorain, Somsubhra Nath, Gopal C. Kundu, Susanta Roychoudhury
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Oncology
Subjects:
mir-146a
β-catenin
Wnt-AKT signalling
CD24
stemness
OSCC
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.651692/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.651692/full

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