Microarray analysis of the <it>in vivo </it>sequence preferences of a minor groove binding drug

<p>Abstract</p> <p>Background</p> <p>Minor groove binding drugs (MGBDs) interact with DNA in a sequence-specific manner and can cause changes in gene expression at the level of transcription. They serve as valuable models for protein interactions with DNA and form an im...

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Bibliographic Details
Main Authors: Malloy Kelly J, Hart Steven N, Brown Adam D, Eckdahl Todd T, Shott Martha, Yiu Gloria, Hoopes Laura, Heyer Laurie J
Format: Article
Language:English
Published: BMC 2008-01-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/9/32