Positive end-expiratory pressure in COVID-19 acute respiratory distress syndrome: the heterogeneous effects

Abstract Background We hypothesized that as CARDS may present different pathophysiological features than classic ARDS, the application of high levels of end-expiratory pressure is questionable. Our first aim was to investigate the effects of 5–15 cmH2O of PEEP on partitioned respiratory mechanics, g...

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Bibliographic Details
Main Authors: Davide Chiumello, Matteo Bonifazi, Tommaso Pozzi, Paolo Formenti, Giuseppe Francesco Sferrazza Papa, Gabriele Zuanetti, Silvia Coppola
Format: Article
Language:English
Published: BMC 2021-12-01
Series:Critical Care
Subjects:
Online Access:https://doi.org/10.1186/s13054-021-03839-4