Targeted Lipidomics of Mitochondria in a Cellular Alzheimer’s Disease Model

Targeted Lipidomics of Mitochondria in a Cellular Alzheimer’s Disease Model

Alzheimer’s disease (AD) is neuropathologically characterized by the accumulation of Amyloid-β (Aβ) in senile plaques derived from amyloidogenic processing of a precursor protein (APP). Recently, changes in mitochondrial function have become in the focus of the disease. Whereas a link between AD and...

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Bibliographic Details
Main Authors: Irina Kurokin, Anna Andrea Lauer, Daniel Janitschke, Jakob Winkler, Elena Leoni Theiss, Lea Victoria Griebsch, Sabrina Melanie Pilz, Veronika Matschke, Martin van der Laan, Heike Sabine Grimm, Tobias Hartmann, Marcus Otto Walter Grimm
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Biomedicines
Subjects:
mitochondria
Alzheimer’s disease
neurodegeneration
lipidomics
unsaturated fatty acids
phosphatidylcholine
Online Access:https://www.mdpi.com/2227-9059/9/8/1062

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https://www.mdpi.com/2227-9059/9/8/1062

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