Stochastic chain termination in bacterial pilus assembly

Abstract Adhesive type 1 pili from uropathogenic Escherichia coli strains are filamentous, supramolecular protein complexes consisting of a short tip fibrillum and a long, helical rod formed by up to several thousand copies of the major pilus subunit FimA. Here, we reconstituted the entire type 1 pi...

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Bibliographic Details
Main Authors: Christoph Giese, Chasper Puorger, Oleksandr Ignatov, Zuzana Bečárová, Marco E. Weber, Martin A. Schärer, Guido Capitani, Rudi Glockshuber
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-43449-y