Effects of the selective inhibition of proteasome caspase-like activity by CLi a derivative of nor-cerpegin in dystrophic mdx mice.

Effects of the selective inhibition of proteasome caspase-like activity by CLi a derivative of nor-cerpegin in dystrophic mdx mice.

Previous studies have shown that proteasome inhibition can have beneficial effects in dystrophic mouse models. In this study, we have investigated the effects of a new selective proteasome inhibitor, CLi, a strong caspase-like inhibitor of the 20S proteasome, on skeletal and cardiac muscle functions...

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Bibliographic Details
Main Authors: Yeranuhi Hovhannisyan, Gagik Melikyan, Nathalie Mougenot, Jacqueline Gao-Li, Bertrand Friguet, Denise Paulin, Zhenlin Li, Arnaud Ferry, Onnik Agbulut
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0215821

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https://doi.org/10.1371/journal.pone.0215821

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