Toxoplasma gondii dense granule protein 15 induces apoptosis in choriocarcinoma JEG-3 cells through endoplasmic reticulum stress

Toxoplasma gondii dense granule protein 15 induces apoptosis in choriocarcinoma JEG-3 cells through endoplasmic reticulum stress

Abstract Background Toxoplasma gondii, a single-celled parasite commonly found in mammals, has been shown to induce trophoblast cell apoptosis and subsequently cause fetal damage and abortion. Although dense granule protein 15 (GRA15) has been identified as a key component in innate immunity to T. g...

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Bibliographic Details
Main Authors: Wei Wei, Fangfang Zhang, He Chen, Yuanyuan Tang, Tian Xing, Qingli Luo, Li Yu, Jian Du, Jilong Shen, Linjie Zhang
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Parasites & Vectors
Subjects:
Toxoplasma gondii
GRA15
Apoptosis
ERS
JEG-3 cell
Online Access:http://link.springer.com/article/10.1186/s13071-018-2835-3

Internet

http://link.springer.com/article/10.1186/s13071-018-2835-3

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