Poxviruses package viral redox proteins in lateral bodies and modulate the host oxidative response.

Poxviruses package viral redox proteins in lateral bodies and modulate the host oxidative response.

All poxviruses contain a set of proteinaceous structures termed lateral bodies (LB) that deliver viral effector proteins into the host cytosol during virus entry. To date, the spatial proteotype of LBs remains unknown. Using the prototypic poxvirus, vaccinia virus (VACV), we employed a quantitative...

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Bibliographic Details
Main Authors: Susanna R Bidgood, Jerzy Samolej, Karel Novy, Abigail Collopy, David Albrecht, Melanie Krause, Jemima J Burden, Bernd Wollscheid, Jason Mercer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-07-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1010614

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https://doi.org/10.1371/journal.ppat.1010614

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