Protopanaxadiol and Protopanaxatriol-Type Saponins Ameliorate Glucose and Lipid Metabolism in Type 2 Diabetes Mellitus in High-Fat Diet/Streptozocin-Induced Mice

Protopanaxadiol and Protopanaxatriol-Type Saponins Ameliorate Glucose and Lipid Metabolism in Type 2 Diabetes Mellitus in High-Fat Diet/Streptozocin-Induced Mice

Ginsenoside is a major active component of ginseng, which exhibits various pharmacological properties such as hepatoprotection, tumor suppression and diabetes resistance. In this study, the anti-diabetic effects of protopanaxadiol (PPD) and protopanaxatriol (PPT)-type saponins were explored and comp...

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Bibliographic Details
Main Authors: Jianjun Deng, Yao Liu, Zhiguang Duan, Chenhui Zhu, Junfeng Hui, Yu Mi, Pei Ma, Xiaoxuan Ma, Daidi Fan, Haixia Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Pharmacology
Subjects:
protopanaxadiol-type saponins
protopanaxatriol-type saponins
type 2 diabetes mellitus
inflammation
glucose metabolism
lipid metabolism
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00506/full

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http://journal.frontiersin.org/article/10.3389/fphar.2017.00506/full

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