Immunosuppression via adenosine receptor activation by adenosine monophosphate released from apoptotic cells

Apoptosis is coupled with recruitment of macrophages for engulfment of dead cells, and with compensatory proliferation of neighboring cells. Yet, this death process is silent, and it does not cause inflammation. The molecular mechanisms underlying anti-inflammatory nature of the apoptotic process re...

Full description

Bibliographic Details
Main Authors: Hiroshi Yamaguchi, Toshihiko Maruyama, Yoshihiro Urade, Shigekazu Nagata
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-03-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/02172