Activation of CXCL12-CXCR4 signalling induces conversion of immortalised embryonic kidney cells into cancer stem-like cells

AbstractCancer stem cells (CSCs) have been implicated in the growth and progression of several types of human cancer. The technology to derive and establish CSCs in vitro could be a critical tool for understanding cancer and developing new therapeutic targets. In this study, we derived expandable CD...

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Bibliographic Details
Main Authors: Seung-ick Oh, Hyesun Jeong, Hang-soo Park, Kyung-Ah Choi, Insik Hwang, Jiyun Lee, Jeonghee Cho, Sunghoi Hong
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Artificial Cells, Nanomedicine, and Biotechnology
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/21691401.2020.1841783