Activation of CXCL12-CXCR4 signalling induces conversion of immortalised embryonic kidney cells into cancer stem-like cells

Activation of CXCL12-CXCR4 signalling induces conversion of immortalised embryonic kidney cells into cancer stem-like cells

Cancer stem cells (CSCs) have been implicated in the growth and progression of several types of human cancer. The technology to derive and establish CSCs in vitro could be a critical tool for understanding cancer and developing new therapeutic targets. In this study, we derived expandable CD15+ indu...

Full description

Bibliographic Details
Main Authors: Seung-ick Oh, Hyesun Jeong, Hang-soo Park, Kyung-Ah Choi, Insik Hwang, Jiyun Lee, Jeonghee Cho, Sunghoi Hong
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Artificial Cells, Nanomedicine, and Biotechnology
Subjects:
iCSCs
BM-MSC
293FT
CXCR4/CXCL12
ERK/ELK1
AKT/STAT3
Online Access:https://www.tandfonline.com/doi/10.1080/21691401.2020.1841783

Similar Items

Similar Items