A Mass Spectrometry-Based Proteome Study of Twin Pairs Discordant for Incident Acute Myocardial Infarction within Three Years after Blood Sampling Suggests Novel Biomarkers

A Mass Spectrometry-Based Proteome Study of Twin Pairs Discordant for Incident Acute Myocardial Infarction within Three Years after Blood Sampling Suggests Novel Biomarkers

Acute myocardial infarction (AMI) is a major cause of mortality and morbidity worldwide, yet biomarkers for AMI in the short- or medium-term are lacking. We apply the discordant twin pair design, reducing genetic and environmental confounding, by linking nationwide registry data on AMI diagnoses to...

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Bibliographic Details
Main Authors: Hans Christian Beck, Asmus Cosmos Skovgaard, Afsaneh Mohammadnejad, Nicolai Bjødstrup Palstrøm, Palle Fruekilde Nielsen, Jonas Mengel-From, Jacob Hjelmborg, Lars Melholt Rasmussen, Mette Soerensen
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:International Journal of Molecular Sciences
Subjects:
acute myocardial infarction
tandem mass spectrometry
proteome-wide association analysis
discordant twin pairs
Online Access:https://www.mdpi.com/1422-0067/25/5/2638

Internet

https://www.mdpi.com/1422-0067/25/5/2638

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