Novel N′-substituted benzylidene benzohydrazides linked to 1,2,3-triazoles: potent α-glucosidase inhibitors

Abstract Herein, various N′-substituted benzylidene benzohydrazide-1,2,3-triazoles were designed, synthesized, and screened for their inhibitory activity toward α-glucosidase. The structure of derivatives was confirmed using 1H- and 13C-NMR, FTIR, Mass spectrometry, and elemental analysis. All deriv...

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Bibliographic Details
Main Authors: Mina Saeedi, Roshanak Hariri, Aida Iraji, Ali Ahmadi, Somayeh Mojtabavi, Shiva Golshani, Mohammad Ali Faramarzi, Tahmineh Akbarzadeh
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-36046-y