CX3 chemokine receptor 1 defciency leads to reduced dendritic complexity and delayed maturation of newborn neurons in the adult mouse hippocampus

Previous studies have shown that microglia impact the proliferation and differentiation of neurons during hippocampal neurogenesis via the fractalkine/CX3 chemokine receptor 1 (CX3CR1) signaling pathway. However, whether microglia can influence the maturation and dendritic growth of newborn neurons...

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Bibliographic Details
Main Authors:	Feng Xiao, Jun-mei Xu, Xing-hua Jiang
Format:	Article
Language:	English
Published:	Wolters Kluwer Medknow Publications 2015-01-01
Series:	Neural Regeneration Research
Subjects:	active zone stability Drosophila neuromuscular junction dephosphorylation Liprin-α Syd-1 PP2A GSK-3ß living scaffolds neural tissue engineering cell transplant biomaterials regeneration neurotrauma neurodegeneration axon pathfinding cell migration injury plasticity neurodegenerative disease brain therapy neuron microglia neural progenitor tissue engineering neuroregeneration repair central nervous system biomaterial regenerative medicine nanotechnology spinal cord injury axonal regeneration exosome extracellular vesicle microRNA microvesicle nerve gap neurite outgrowth peripheral nerve injury Schwann cell stem cell hemodynamic phases cerebral subarachnoid hemorrhage metabolic crises nerve regeneration hypoxic-ischemic brain damage ginsenoside Rg1 neural stem cells cell transplantation cell differentiation cognition nerve reconstruction neural regeneration brain injury neuroimaging functional magnetic resonance imaging regional homogeneity apoplexy subacute ischemia participants healthy volunteers brain activity NSFC grants neuroprotection cerebral ischemia/reperfusion injury lateral intracerebroventricular injection Apelin-13 nerve apoptosis Bcl-2 caspase-3 fractalkine CX3 chemokine receptor 1 neuronal maturation dendrites doublecortin synaptic maturation newborn neurons
Online Access:	http://www.nrronline.org/article.asp?issn=1673-5374;year=2015;volume=10;issue=5;spage=772;epage=777;aulast=Xiao

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2015;volume=10;issue=5;spage=772;epage=777;aulast=Xiao

CX3 chemokine receptor 1 defciency leads to reduced dendritic complexity and delayed maturation of newborn neurons in the adult mouse hippocampus

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