Induction of apoptosis in cells expressing exogenous Hippi, a molecular partner of huntingtin-interacting protein Hip1

Induction of apoptosis in cells expressing exogenous Hippi, a molecular partner of huntingtin-interacting protein Hip1

To decipher the pathway of apoptosis induction downstream to caspase-8 activation by exogenous expression of Hippi, an interactor of huntingtin-interacting protein Hip1, we studied apoptosis in HeLa and Neuro2A cells expressing GFP-tagged Hippi. Nuclear fragmentation, caspase-1, caspase-8, caspase-9...

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Bibliographic Details
Main Authors: Pritha Majumder, Biswanath Chattopadhyay, Arindam Mazumder, Pradeep Das, Nitai P. Bhattacharyya
Format: Article
Language:English
Published: Elsevier 2006-05-01
Series:Neurobiology of Disease
Subjects:
Hippi
HIP1
Apoptosis
Cytochrome c
AIF
Caspase expression
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996105003062

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http://www.sciencedirect.com/science/article/pii/S0969996105003062

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