TMEM16B regulates anxiety-related behavior and GABAergic neuronal signaling in the central lateral amygdala
TMEM16B (ANO2) is the Ca2+-activated chloride channel expressed in multiple brain regions, including the amygdala. Here we report that Ano2 knockout mice exhibit impaired anxiety-related behaviors and context-independent fear memory, thus implicating TMEM16B in anxiety modulation. We found that TMEM...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Jezik: | English |
| Izdano: |
eLife Sciences Publications Ltd
2019-09-01
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| Serija: | eLife |
| Teme: | |
| Online dostop: | https://elifesciences.org/articles/47106 |