Continuous sensing of nutrients and growth factors by the mTORC1-TFEB axis
mTORC1 senses nutrients and growth factors and phosphorylates downstream targets, including the transcription factor TFEB, to coordinate metabolic supply and demand. These functions position mTORC1 as a central controller of cellular homeostasis, but the behavior of this system in individual cells h...
| Үндсэн зохиолчид: | , , , , , |
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| Формат: | Өгүүллэг |
| Хэл сонгох: | English |
| Хэвлэсэн: |
eLife Sciences Publications Ltd
2023-09-01
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| Цуврал: | eLife |
| Нөхцлүүд: | |
| Онлайн хандалт: | https://elifesciences.org/articles/74903 |