Functional Evaluation and Nephrotoxicity Assessment of Human Renal Proximal Tubule Cells on a Chip

An in vitro human renal proximal tubule model that represents the proper transporter expression and pronounced epithelial polarization is necessary for the accurate prediction of nephrotoxicity. Here, we constructed a high-throughput human renal proximal tubule model based on an integrated biomimeti...

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Bibliographic Details
Main Authors: Bolin Jing, Lei Yan, Jiajia Li, Piaopiao Luo, Xiaoni Ai, Pengfei Tu
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Biosensors
Subjects:
Online Access:https://www.mdpi.com/2079-6374/12/9/718