Artificial intelligence guided discovery of a barrier-protective therapy in inflammatory bowel disease

Artificial intelligence guided discovery of a barrier-protective therapy in inflammatory bowel disease

Traditional drug discovery process use differential, Bayesian and other network based approaches. We developed a Boolean approach for building disease maps and prioritizing pre-clinical models to discover a first-in-class therapy to restore and protect the leaky gut barrier in inflammatory bowel dis...

Full description

Bibliographic Details
Main Authors: Debashis Sahoo, Lee Swanson, Ibrahim M. Sayed, Gajanan D. Katkar, Stella-Rita Ibeawuchi, Yash Mittal, Rama F. Pranadinata, Courtney Tindle, Mackenzie Fuller, Dominik L. Stec, John T. Chang, William J. Sandborn, Soumita Das, Pradipta Ghosh
Format: Article
Language:English
Published: Nature Portfolio 2021-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-24470-5

Internet

https://doi.org/10.1038/s41467-021-24470-5

Similar Items