Systematic engineering pinpoints a versatile strategy for the expression of functional cytochrome P450 enzymes in Escherichia coli cell factories

Abstract Production of plant secondary metabolites in engineered microorganisms provides a scalable and sustainable alternative to their sourcing from nature or through chemical synthesis. However, the biosynthesis of many valuable plant-derived products relies on cytochromes P450 – enzymes notoriou...

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Bibliographic Details
Main Authors: Michal Poborsky, Christoph Crocoll, Mohammed Saddik Motawie, Barbara Ann Halkier
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Microbial Cell Factories
Online Access:https://doi.org/10.1186/s12934-023-02219-7