Structural insights into the broad protection against H1 influenza viruses by a computationally optimized hemagglutinin vaccine

Structural insights into the broad protection against H1 influenza viruses by a computationally optimized hemagglutinin vaccine

Abstract Influenza virus poses an ongoing human health threat with pandemic potential. Due to mutations in circulating strains, formulating effective vaccines remains a challenge. The use of computationally optimized broadly reactive antigen (COBRA) hemagglutinin (HA) proteins is a promising vaccine...

Full description

Bibliographic Details
Main Authors: John V. Dzimianski, Julianna Han, Giuseppe A. Sautto, Sara M. O’Rourke, Joseph M. Cruz, Spencer R. Pierce, Jeffrey W. Ecker, Michael A. Carlock, Kaito A. Nagashima, Jarrod J. Mousa, Ted M. Ross, Andrew B. Ward, Rebecca M. DuBois
Format: Article
Language:English
Published: Nature Portfolio 2023-04-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-04793-3

Internet

https://doi.org/10.1038/s42003-023-04793-3

Similar Items