Location of the hydrophobic pocket in the binding site of fentanyl analogs in the µ-opioid receptor

Fentanyl is a highly potent and clinically widely used narcotic analgesic. The synthesis of its analogs remains a challenge in an attempt to develop highly selective µ-opioid receptor agonists with specific pharmacological properties. In this paper, the use of flexible molecular docking of several s...

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Bibliographic Details
Main Authors: Došen-Mićović Ljiljana, Ivanović Milovan, Mićović Vuk
Format: Article
Language:English
Published: Serbian Chemical Society 2007-01-01
Series:Journal of the Serbian Chemical Society
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/0352-5139/2007/0352-51390707643D.pdf