Location of the hydrophobic pocket in the binding site of fentanyl analogs in the µ-opioid receptor
Fentanyl is a highly potent and clinically widely used narcotic analgesic. The synthesis of its analogs remains a challenge in an attempt to develop highly selective µ-opioid receptor agonists with specific pharmacological properties. In this paper, the use of flexible molecular docking of several s...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Serbian Chemical Society
2007-01-01
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Series: | Journal of the Serbian Chemical Society |
Subjects: | |
Online Access: | http://www.doiserbia.nb.rs/img/doi/0352-5139/2007/0352-51390707643D.pdf |