Minor Role of Plasminogen in Complement Activation on Cell Surfaces.

Atypical hemolytic uremic syndrome (aHUS) is a rare, but severe thrombotic microangiopathy. In roughly two thirds of the patients, mutations in complement genes lead to uncontrolled activation of the complement system against self cells. Recently, aHUS patients were described with deficiency of the...

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Bibliographic Details
Main Authors: Satu Hyvärinen, T Sakari Jokiranta
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4670116?pdf=render