Of mice and men: Laboratory murine models for recapitulating the immunosuppression of human sepsis

Prolonged immunosuppression is increasingly recognized as the major cause of late phase and long-term mortality in sepsis. Numerous murine models with different paradigms, such as lipopolysaccharide injection, bacterial inoculation, and barrier disruption, have been used to explore the pathogenesis...

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Bibliographic Details
Main Authors: Ning Wang, Yongling Lu, Jiang Zheng, Xin Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.956448/full