A Marine Analgesic Peptide, Contulakin-G, and Neurotensin are Distinct Agonists for Neurotensin Receptors: Uncovering Structural Determinants of Desensitization Properties
Neurotensin receptors have been studied as molecular targets for the treatment of pain, schizophrenia, addiction, or cancer. Neurotensin (NT) and Contulakin-G, a glycopeptide isolated from a predatory cone snail Conus geographus, share a sequence similarity at the C-terminus, which is critical for a...
Egile Nagusiak: | , , , , , , , , , |
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Formatua: | Artikulua |
Hizkuntza: | English |
Argitaratua: |
Frontiers Media S.A.
2015-02-01
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Saila: | Frontiers in Pharmacology |
Gaiak: | |
Sarrera elektronikoa: | http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00011/full |