Gellan-Based Composite System as a Potential Tool for the Treatment of Nervous Tissue Injuries: Cross-Linked Electrospun Nanofibers Embedded in a RC-33-Loaded Freeze-Dried Matrix

Gellan-Based Composite System as a Potential Tool for the Treatment of Nervous Tissue Injuries: Cross-Linked Electrospun Nanofibers Embedded in a RC-33-Loaded Freeze-Dried Matrix

Injuries to the nervous system affect more than one billion people worldwide, and dramatically impact on the patient’s quality of life. The present work aimed to design and develop a gellan gum (GG)-based composite system for the local delivery of the neuroprotective sigma-1 receptor agonist, 1-[3-(...

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Bibliographic Details
Main Authors: Barbara Vigani, Caterina Valentino, Valeria Cavalloro, Laura Catenacci, Milena Sorrenti, Giuseppina Sandri, Maria Cristina Bonferoni, Chiara Bozzi, Simona Collina, Silvia Rossi, Franca Ferrari
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Pharmaceutics
Subjects:
nervous tissue injuries
gellan gum
S1R agonist
electrospinning
nanofibers
cross-linking
Online Access:https://www.mdpi.com/1999-4923/13/2/164

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https://www.mdpi.com/1999-4923/13/2/164

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