Synthesis of Non-proteinogenic Amino-Acid Methyl Esters with Acid-Sensitive Side Chains from a Chiral Glycine Derivative
A superior chiral glycine derivative 1 (tert-butyl 2-(tert-butyl)-4-methoxy-2,5-dihydro-1,3-imidazole-1-carboxylate, BDI) for the synthesis of acid-sensitive and highly hindered ?-amino-acid methyl esters is readily available by resolution methods. The heterocycle 1 is alkylated once and t...
| Main Authors: | , |
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| Format: | Article |
| Language: | deu |
| Published: |
Swiss Chemical Society
1997-03-01
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| Series: | CHIMIA |
| Online Access: | https://www.chimia.ch/chimia/article/view/2807 |