Promising PEGylated cationic dendrimers for delivery of miRNAs as a possible therapy against HIV-1 infection

Promising PEGylated cationic dendrimers for delivery of miRNAs as a possible therapy against HIV-1 infection

Abstract Background The appearance of resistance against new treatments and the fact that HIV-1 can infect various cell types and develop reservoirs and sanctuaries makes it necessary to develop new therapeutic approaches to overcome those failures. Results Studies of cytotoxicity, genotoxicity, com...

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Bibliographic Details
Main Authors: E. Royo-Rubio, I. Rodríguez-Izquierdo, M. Moreno-Domene, T. Lozano-Cruz, F. J. de la Mata, R. Gómez, M. A. Muñoz-Fernández, J. L. Jiménez
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Journal of Nanobiotechnology
Subjects:
Carbosilane dendrimers
microRNAs
HIV-1 infection
Delivery
Inhibition
Online Access:https://doi.org/10.1186/s12951-021-00899-0

Internet

https://doi.org/10.1186/s12951-021-00899-0

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