Myeloid CCN3 protects against aortic valve calcification

Myeloid CCN3 protects against aortic valve calcification

Abstract Background Cellular communication network factor 3 (CCN3) has been implicated in the regulation of osteoblast differentiation. However, it is not known if CCN3 can regulate valvular calcification. While macrophages have been shown to regulate valvular calcification, the molecular and cellul...

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Bibliographic Details
Main Authors: Peinan Tu, Qian Xu, Xianming Zhou, Nicolas Villa-Roel, Sandeep Kumar, Nianguo Dong, Hanjoong Jo, Caiwen Ou, Zhiyong Lin
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Cell Communication and Signaling
Subjects:
Myeloid
Macrophage CCN3
Valvular calcification
BMP2
Online Access:https://doi.org/10.1186/s12964-022-01020-0

Internet

https://doi.org/10.1186/s12964-022-01020-0

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