Polymorphisms in <i>ACE1</i>, <i>TMPRSS2</i>, <i>IFIH1</i>, <i>IFNAR2</i>, and <i>TYK2</i> Genes Are Associated with Worse Clinical Outcomes in COVID-19

Polymorphisms in <i>ACE1</i>, <i>TMPRSS2</i>, <i>IFIH1</i>, <i>IFNAR2</i>, and <i>TYK2</i> Genes Are Associated with Worse Clinical Outcomes in COVID-19

Although advanced age, male sex, and some comorbidities impact the clinical course of COVID-19, these factors only partially explain the inter-individual variability in disease severity. Some studies have shown that genetic polymorphisms contribute to COVID-19 severity; however, the results are inco...

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Bibliographic Details
Main Authors: Cristine Dieter, Leticia de Almeida Brondani, Natália Emerim Lemos, Ariell Freires Schaeffer, Caroline Zanotto, Denise Taurino Ramos, Eliandra Girardi, Felipe Mateus Pellenz, Joiza Lins Camargo, Karla Suzana Moresco, Lucas Lima da Silva, Mariana Rauback Aubin, Mayara Souza de Oliveira, Tatiana Helena Rech, Luís Henrique Canani, Fernando Gerchman, Cristiane Bauermann Leitão, Daisy Crispim
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Genes
Subjects:
polymorphisms
SARS-CoV-2
COVID-19
<i>ACE1</i>
<i>IFIH1</i>
<i>IFNAR2</i>
Online Access:https://www.mdpi.com/2073-4425/14/1/29

Internet

https://www.mdpi.com/2073-4425/14/1/29

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