Impact of the amount of PEG on prodrug nanoassemblies for efficient cancer therapy

Impact of the amount of PEG on prodrug nanoassemblies for efficient cancer therapy

PEGylation has been widely used to improve the pharmacokinetic properties of prodrug self-assembled nanoparticles (prodrug-SANPs). However, the impacts of the amount of PEG on the self-assemble stability, cellular uptake, pharmacokinetics, and antitumor efficacy of prodrug-SANPs are still unknown. H...

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Bibliographic Details
Main Authors: Yaqiao Li, Lingxiao Li, Qianhui Jin, Tian Liu, Jin Sun, Yongjun Wang, Zhijun Yang, Zhonggui He, Bingjun Sun
Format: Article
Language:English
Published: Elsevier 2022-03-01
Series:Asian Journal of Pharmaceutical Sciences
Subjects:
PEGylation
Prodrug
Self-assembly nanoparticles
Docetaxel
Oxidation responsive
Online Access:http://www.sciencedirect.com/science/article/pii/S1818087622000174

Internet

http://www.sciencedirect.com/science/article/pii/S1818087622000174

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