Translation control can shape TP53-dependent cell fate

Translation control can shape TP53-dependent cell fate

The search for mechanisms underlying different cellular responses to the treatment with Nutlin-3, an MDM2 inhibitor that unleashes p53, revealed a translational control mechanism involving the RNA binding proteins PCBP2 and, particularly, DHX30. Sifting through a multi-functional p53-dependent trans...

Bibliografske podrobnosti
Main Authors:	Dario Rizzotto, Sara Zaccara, Annalisa Rossi, Erik Dassi, Alberto Inga
Format:	Article
Jezik:	English
Izdano:	Taylor & Francis Group 2020-09-01
Serija:	Molecular & Cellular Oncology
Teme:	p53 dhx30 pcbp2 apoptosis transcription translation polysomal profiling translatome
Online dostop:	http://dx.doi.org/10.1080/23723556.2020.1767483

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