Contribution of low population immunity to the severe Omicron BA.2 outbreak in Hong Kong

Hong Kong experienced a severe wave of SARS-CoV-2 in early 2022. Here, the authors use genomic and serosurveillance data and show that this wave was dominated by the Omicron BA.2 sublineage, and that low protective immunity, particularly in older age groups, contributed to its severity.

Bibliographic Details
Main Authors: Lin-Lei Chen, Syed Muhammad Umer Abdullah, Wan-Mui Chan, Brian Pui-Chun Chan, Jonathan Daniel Ip, Allen Wing-Ho Chu, Lu Lu, Xiaojuan Zhang, Yan Zhao, Vivien Wai-Man Chuang, Albert Ka-Wing Au, Vincent Chi-Chung Cheng, Siddharth Sridhar, Kwok-Yung Yuen, Ivan Fan-Ngai Hung, Kwok-Hung Chan, Kelvin Kai-Wang To
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-31395-0