Direct Analysis of Mitochondrial Damage Caused by Misfolded/Destabilized Proteins

Direct Analysis of Mitochondrial Damage Caused by Misfolded/Destabilized Proteins

Protein quality control is essential for cellular homeostasis. In this study, we examined the effect of improperly folded proteins that do not form amyloid fibrils on mitochondria, which play important roles in ATP production and cell death. First, we prepared domain 3 of the dengue envelope protein...

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Bibliographic Details
Main Authors: Jannatul Aklima, Sawaros Onchaiya, Tomonori Saotome, Punitha Velmurugan, Taihei Motoichi, Jannatul Naima, Yutaka Kuroda, Yoshihiro Ohta
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:International Journal of Molecular Sciences
Subjects:
dengue envelope protein domain 3
membrane
mitochondria
misfolded protein
thermal instability
Online Access:https://www.mdpi.com/1422-0067/23/17/9881

Internet

https://www.mdpi.com/1422-0067/23/17/9881

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