Development of an Automated and Sensitive Microfluidic Device for Capturing and Characterizing Circulating Tumor Cells (CTCs) from Clinical Blood Samples.

Current analysis of circulating tumor cells (CTCs) is hindered by sub-optimal sensitivity and specificity of devices or assays as well as lack of capability of characterization of CTCs with clinical biomarkers. Here, we validate a novel technology to enrich and characterize CTCs from blood samples o...

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Bibliographic Details
Main Authors: Priya Gogoi, Saedeh Sepehri, Yi Zhou, Michael A Gorin, Carmela Paolillo, Ettore Capoluongo, Kyle Gleason, Austin Payne, Brian Boniface, Massimo Cristofanilli, Todd M Morgan, Paolo Fortina, Kenneth J Pienta, Kalyan Handique, Yixin Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4726586?pdf=render