Artificial selection for whole animal low intrinsic aerobic capacity co-segregates with hypoxia-induced cardiac pump failure.

Oxygen metabolism is a strong predictor of the general health and fitness of an organism. In this study, we hypothesized that a divergence in intrinsic aerobic fitness would co-segregate with susceptibility for cardiovascular dysfunction. To test this hypothesis, cardiac function was assessed in rat...

Full description

Bibliographic Details
Main Authors: Nathan J Palpant, Michael L Szatkowski, Wang Wang, DeWayne Townsend, Fikru B Bedada, Lauren G Koch, Steven L Britton, Joseph M Metzger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2699480?pdf=render