Analysis of the dihydrofolate reductase-thymidylate synthase gene sequences in <it>Plasmodium vivax </it>field isolates that failed chloroquine treatment

Analysis of the dihydrofolate reductase-thymidylate synthase gene sequences in <it>Plasmodium vivax </it>field isolates that failed chloroquine treatment

<p>Abstract</p> <p>Background</p> <p>To use pyrimethamine as an alternative anti-malarial drug for chloroquine-resistant malaria parasites, it was necessary to determine the enzyme's genetic variation in dihydrofolate reductase-thymidylate syntase (DHFR-TS) among K...

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Bibliographic Details
Main Authors: Kim Hyuck, Sohn Youngjoo, Sattabongkot Jetsumon, Kim Jung-Yeon, Kim Mi-A, Choi Kyung-Mi, Choi Yien-Kyoung, Kim Hyung-Hwan, Lee Won-Ja, Lee Jong-Koo, Park Han-Sook, Lee Hyeong-Woo
Format: Article
Language:English
Published: BMC 2010-11-01
Series:Malaria Journal
Online Access:http://www.malariajournal.com/content/9/1/331

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http://www.malariajournal.com/content/9/1/331

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