A curated benchmark of enhancer-gene interactions for evaluating enhancer-target gene prediction methods

Abstract Background Many genome-wide collections of candidate cis-regulatory elements (cCREs) have been defined using genomic and epigenomic data, but it remains a major challenge to connect these elements to their target genes. Results To facilitate the development of computational methods for pred...

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Bibliographic Details
Main Authors: Jill E. Moore, Henry E. Pratt, Michael J. Purcaro, Zhiping Weng
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Genome Biology
Subjects:
Online Access:https://doi.org/10.1186/s13059-019-1924-8