Caspase-1 Regulates the Apoptosis and Pyroptosis Induced by Phthalocyanine Zinc-Mediated Photodynamic Therapy in Breast Cancer MCF-7 Cells

Caspase-1 Regulates the Apoptosis and Pyroptosis Induced by Phthalocyanine Zinc-Mediated Photodynamic Therapy in Breast Cancer MCF-7 Cells

Photodynamic therapy (PDT) is an innovative and perspective antineoplastic therapy. Tetra-α-(4-carboxyphenoxy) phthalocyanine zinc (TαPcZn)-mediated PDT (TαPcZn-PDT) has shown antitumor activity in some tumor cells, but the manner in which caspase-1 is involved in the regulation of apoptosis and pyr...

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Bibliographic Details
Main Authors: Chunjie Ma, Yu Wang, Wei Chen, Ting Hou, Honglian Zhang, Hongguang Zhang, Xu Yao, Chunhui Xia
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Molecules
Subjects:
TαPcZn-PDT
ROS
apoptosis
pyroptosis
siRNA-caspase-1
Online Access:https://www.mdpi.com/1420-3049/28/16/5934

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https://www.mdpi.com/1420-3049/28/16/5934

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