The Role of Autophagy in Glaucomatous Optic Neuropathy

Autophagy is a conserved lysosomal-dependent pathway responsible for the degradation of cytoplasmic macromolecules. Based on the mechanism of cargo delivery to lysosomes, mammalian cells can undergo micro, macro, and chaperone-mediated autophagy. Other than physiological turnover of proteins and org...

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Bibliographic Details
Main Authors: Annagrazia Adornetto, Vincenzo Parisi, Luigi Antonio Morrone, Maria Tiziana Corasaniti, Giacinto Bagetta, Paolo Tonin, Rossella Russo
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00121/full