Small, Smaller, Smallest: Minimal Structural Requirements for a Fully Functional Box C/D Modification Guide RNA

Site-specific 2&#8217;-<i>O</i>-ribose methylation is an abundant post-transcriptional modification mediated by small non-coding nuclear RNAs known as box C/D modification guide RNAs. The minimal structural requirements for these guide RNAs to function in higher eukaryotes are still...

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Bibliographic Details
Main Authors: Svetlana Deryusheva, Joseph G. Gall
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/9/9/457