Macrophage migration inhibitory factor receptor CD74 expression is associated with expansion and differentiation of effector T cells in COVID-19 patients

Macrophage migration inhibitory factor receptor CD74 expression is associated with expansion and differentiation of effector T cells in COVID-19 patients

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused millions of COVID-19 cases and deaths worldwide. Severity of pulmonary pathologies and poor prognosis were reported to be associated with the activation non-virus-specific bystander T cells. In addition, high concentrations of the m...

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Bibliographic Details
Main Authors: Jaana Westmeier, Annika Brochtrup, Krystallenia Paniskaki, Zehra Karakoese, Tanja Werner, Kathrin Sutter, Sebastian Dolff, Andreas Limmer, Daniela Mittermüller, Jia Liu, Xin Zheng, Tetiana Koval, Igor Kaidashev, Marc Moritz Berger, Frank Herbstreit, Thorsten Brenner, Oliver Witzke, Mirko Trilling, Mengji Lu, Dongliang Yang, Nina Babel, Timm Westhoff, Ulf Dittmer, Gennadiy Zelinskyy
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Immunology
Subjects:
COVID-19
SARS-CoV-2
cytotoxic T cells
CD8+
CD4+
MIF
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1236374/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1236374/full

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