Lung Inflammation in STING-Associated Vasculopathy with Onset in Infancy (SAVI)

STING-associated vasculopathy with onset in infancy (SAVI) is a type I interferonopathy caused by gain-of-function mutations in <i>STING1</i> encoding stimulator of interferon genes (STING) protein. SAVI is characterized by severe inflammatory lung disease, a feature not observed in prev...

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Bibliographic Details
Main Authors: Clémence David, Marie-Louise Frémond
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/11/3/318