Bioinformatics-integrated screening of systemic sclerosis-specific expressed markers to identify therapeutic targets

BackgroundSystemic sclerosis (SSc) is a rare autoimmune disease characterized by extensive skin fibrosis. There are no effective treatments due to the severity, multiorgan presentation, and variable outcomes of the disease. Here, integrated bioinformatics was employed to discover tissue-specific exp...

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Bibliographic Details
Main Authors: Jiahui Jin, Yifan Liu, Qinyu Tang, Xin Yan, Miao Jiang, Xu Zhao, Jie Chen, Caixia Jin, Qingjian Ou, Jingjun Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1125183/full